Human Neurons That Reflect Real Disease Progression
Age-defined neurons · Not embryonic-like cells
Capture authentic pathology across disease stages
Preserve Aging Biology
Capture Disease Pathology
Enable Translational Applications
Advancing Neurodegenerative
Disease Research and
Drug Discovery
Human Neurons That Reflect Real Disease Progression
Age-defined neurons · Not embryonic-like cells
Capture authentic pathology across disease stages
Preserve Aging Biology
Capture Disease Pathology
Enable Translational Applications
Advancing Neurodegenerative
Disease Research and
Drug Discovery
Most in vitro models rely on iPSC-derived neurons that resemble embryonic stages, limiting their ability to reproduce late-onset disease features. Our platform generates age-defined human neurons that preserve disease-relevant characteristics, enabling more predictive and translational research.
Why Age Matters in Neurodegeneration Models
Product-Cited Publications
MN203 – Human Motor Neurons
Immunity | 2026
Used to investigate microglia-driven neuroinflammation and TDP-43 pathology in neurodegenerative disease models
✚Customer-Cited
Conducted by a U.S. National Academy of Sciences member–led research team
DN101, DN601 – Human Dopaminergic Neurons
Biotechnology Journal | 2023
Used for immunoblotting analysis of age-associated protein signatures in dopaminergic neuron models
✚Application Study
BFCN601, BFCNAD04 – Human Basal Forebrain Cholinergic Neurons
bioRxiv | 2024
Used to evaluate the efficacy of FDA-approved lecanemab in Alzheimer's disease–relevant models
Access human neuronal models that recapitulate key pathological features of neurodegenerative diseases.
Disease Models
Subtype-specific human neurons generated through Efficient Cell Conversion Technology (ECT) Preserve aging and disease signatures to recapitulate pathology and enable translational drug discovery